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Clinical trials
- Participate in a clinical trial
- For medical professionals
- Active clinical trials for pediatric cancers
- CAR-20/19-T cells in pediatric and young adult patients with relapsed/refractory B Cell Acute Lymphoblastic Leukemia (CAR-20/19-T) phase 1 clinical trial
- Unrelated and partially matched related donor peripheral stem cell transplantation for patients with hematologic malignancies clinical trial
- Early stage research
Active clinical trials
Cancer Clinical Trials - NYMC-571
Protocol Summary
- Protocol No
- NYMC-571
- Principal Investigator
- Julie-An Talano
- Phase
- II
- Title
- The Safety and Efficacy of Prophylactic Defibrotide Administration in Children, Adolescents, and Young Adults with Sickle Cell Disease or Beta Thalassemia Following Myeloablative Conditioning (MAC) and Haploidentical Stem Cell Transplantation Utilizing CD34 Enrichment and T-Cell (CD3) Addback (IND 127812)
- Associated Disease(s)
-
Sickle Cell Disease
- Description (Summary)
- This study seeks to determine if the use of defibrotide prophylaxis during conditioning therapy and up to 30 days post-transplant is safe, well-tolerated, and yields lower incidences of Sinusoidal obstruction syndrome.
- Participating Institutions
- Childrens Hospital of Wisconsin
- ClinicalTrials.gov
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Why participate in clinical trials?
